ERMI panel · 36 species

All 36 mold species tested by ERMI.

The Environmental Relative Moldiness Index (ERMI) panel tests for 26 water-damage indicator species (sometimes labeled “Group 1”) and 10 environmental reference species (Group 2) commonly found in outdoor air. Five of the indicator species form the HERTSMI-2 subset, weighted heavily in building re-entry scoring.

Each profile below covers the species’ biology, mycotoxin production, moisture requirements (water activity, Aw), and what elevated levels typically indicate about indoor conditions.

HERTSMI-2 species

Five water-damage indicator species used in HERTSMI-2 (Health Effects Roster of Type-Specific Formers of Mycotoxins and Inflammagens, version 2). Dr. Ritchie C. Shoemaker designed HERTSMI-2 to inform re-entry decisions for individuals previously sickened in water-damaged environments. Each species has its own scoring thresholds.

Water-damage indicator species

Twenty-six species selected by EPA researchers for their statistical association with water-damaged buildings in the American Healthy Homes Surveys. These are the species more strongly tied to indoor moisture problems than to normal outdoor air, so an indoor elevation is the kind of finding worth investigating. (EPA documentation labels these “Group 1.”)

Aspergillus flavus/oryzae

Xerophilic

Aw ≥ 0.78·Primary colonizer

Aspergillus flavus is one of the most significant toxigenic molds on the ERMI panel.

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Aspergillus fumigatus

Mesophilic

Aw ≥ 0.82·Secondary colonizer

Aspergillus fumigatus is the single most important mold pathogen for immunocompromised individuals, responsible for the large majority of invasive aspergillosis cases, a life-thre…

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Aspergillus niger

Xerophilic

Aw ≥ 0.77·Primary colonizer

Aspergillus niger is one of the most immediately recognizable indoor molds: the black fuzzy growth found on damp drywall, bathroom grout, and food items like onions and spices.

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Aspergillus ochraceus

Xerophilic

Aw ≥ 0.77·Primary colonizer

Aspergillus ochraceus is a xerophilic mold best known as a producer of ochratoxin A, a nephrotoxic (kidney-damaging), immunosuppressive mycotoxin classified by IARC as Group 2B (p…

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Aspergillus penicillioides

H2Xerophilic

Aw ≥ 0.73·Primary colonizer

Aspergillus penicillioides is among the most extreme xerophiles on the ERMI panel, capable of germinating at water activity as low as 0.73 in laboratory conditions and even lower…

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Aspergillus restrictus

Xerophilic

Aw ≥ 0.75·Primary colonizer

Aspergillus restrictus is a slow-growing xerophile closely related to A.

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Aspergillus sclerotiorum

Mesophilic

Aw ≥ 0.80·Secondary colonizer

Aspergillus sclerotiorum belongs to Aspergillus section Circumdati, the same taxonomic group as A.

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Aspergillus sydowii

Xerophilic

Aw ≥ 0.78·Primary colonizer

Aspergillus sydowii is closely related to A.

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Aspergillus unguis

Mesophilic

Aw ≥ 0.83·Secondary colonizer

Aspergillus unguis is a member of Aspergillus section Nidulantes, a group that includes several species associated with water-damaged indoor environments.

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Aspergillus versicolor

H2Xerophilic

Aw ≥ 0.78·Primary colonizer

Aspergillus versicolor is one of the most significant and most common molds found in water-damaged buildings.

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Aureobasidium pullulans

Mesophilic

Aw ≥ 0.88·Secondary colonizer

Aureobasidium pullulans is a remarkable polymorphic fungus that can appear as a yeast, as a filamentous mold, or as a combination of both, ranging in color from white through pink…

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Chaetomium globosum

H2Hydrophilic

Aw ≥ 0.90·Tertiary colonizer

Chaetomium globosum is consistently ranked among the most common indoor molds in water-damaged buildings (often cited as the third most frequently isolated genus after Penicillium…

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Cladosporium sphaerospermum

Mesophilic

Aw ≥ 0.82·Secondary colonizer

Cladosporium sphaerospermum is the most xerotolerant of the indoor Cladosporium species, meaning it can grow at lower moisture levels than C.

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Eurotium (Asp.) amstelodami

Xerophilic

Aw ≥ 0.70·Primary colonizer

Eurotium amstelodami (now often classified under the Aspergillus genus) is one of the most drought-tolerant molds that can colonize indoor environments.

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Paecilomyces variotii

Xerophilic

Aw ≥ 0.79·Primary colonizer

Paecilomyces variotii is a heat-tolerant, xerophilic mold found in damp buildings, HVAC systems, soil, and on a wide variety of organic materials.

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Penicillium brevicompactum

Xerophilic

Aw ≥ 0.78·Primary colonizer

Penicillium brevicompactum is a common xerophilic mold found in damp homes, particularly on gypsum board, walls, and mattresses.

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Penicillium corylophilum

Mesophilic

Aw ≥ 0.80·Secondary colonizer

Penicillium corylophilum is one of the most commonly found Penicillium species in water-damaged buildings, particularly on gypsum board, wallpaper, and interior wood surfaces.

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Penicillium crustosum

Mesophilic

Aw ≥ 0.83·Secondary colonizer

Penicillium crustosum is a common indoor Penicillium species found on water-damaged gypsum board, wallpaper, and other cellulose-containing building materials.

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Penicillium purpurogenum

Mesophilic

Aw ≥ 0.83·Secondary colonizer

Penicillium purpurogenum (reclassified as Talaromyces purpurogenus per Yilmaz et al.

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Penicillium spinulosum/glabrum

Xerophilic

Aw ≥ 0.79·Primary colonizer

Penicillium spinulosum and Penicillium glabrum are closely related primary colonizer Penicillium species found in damp indoor environments.

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Penicillium variabile

Mesophilic

Aw ≥ 0.83·Secondary colonizer

Penicillium variabile is one of the seven Penicillium species on the ERMI panel and is associated with damp indoor environments and water-damaged building materials.

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Scopulariopsis brevicaulis/fusca

Hydrophilic

Aw ≥ 0.90·Tertiary colonizer

Scopulariopsis brevicaulis is historically noted for its ability to methylate arsenic compounds, a widely repeated (though not strongly evidenced in modern primary literature) sto…

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Scopulariopsis chartarum

Hydrophilic

Aw ≥ 0.90·Tertiary colonizer

Scopulariopsis chartarum is a dark-pigmented (dematiaceous) member of the Scopulariopsis genus found in moist indoor environments.

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Stachybotrys chartarum

H2Hydrophilic

Aw ≥ 0.94·Tertiary colonizer

Stachybotrys chartarum (commonly called 'black mold') is the most notorious mold in the context of water-damaged buildings and building-related illness.

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Trichoderma viride

Hydrophilic

Aw ≥ 0.90·Tertiary colonizer

Trichoderma viride is a fast-growing, bright green mold most commonly found on very wet building materials, particularly water-saturated wood, gypsum board, and paint.

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Wallemia sebi

H2Xerophilic

Aw ≥ 0.69·Primary colonizer

Wallemia sebi is one of the most extreme xerophiles in the fungal world, capable of growing on surfaces that most molds would consider far too dry.

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Environmental reference species

Ten species commonly found in outdoor air and routine household dust. Elevated indoor levels of these species usually reflect outdoor-air infiltration or normal dust tracking rather than a water-damage signal. (EPA documentation labels these “Group 2.”)

Acremonium strictum

Hydrophilic

Aw ≥ 0.90·Tertiary colonizer

Acremonium strictum is one of the molds most often found in water-damaged building materials.

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Alternaria alternata

Mesophilic

Aw ≥ 0.85·Secondary colonizer

Alternaria alternata is the outdoor mold most strongly associated with allergic asthma.

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Aspergillus ustus

Mesophilic

Aw ≥ 0.83·Secondary colonizer

Aspergillus ustus is an emerging opportunistic pathogen that has gained attention in clinical settings due to its resistance to multiple antifungal medications, including triazole…

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Cladosporium cladosporioides 1

Mesophilic

Aw ≥ 0.87·Secondary colonizer

Cladosporium cladosporioides is one of the most ubiquitous mold species on the planet, found everywhere from polar regions to tropical environments, and consistently among the mos…

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Cladosporium cladosporioides 2

Mesophilic

Aw ≥ 0.87·Secondary colonizer

The second sequence variant (seqvar 2) of Cladosporium cladosporioides represents a closely related genetic lineage of the same species, separated in the ERMI panel because molecu…

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Cladosporium herbarum

Mesophilic

Aw ≥ 0.85·Secondary colonizer

Cladosporium herbarum is one of the most important mold allergens after Alternaria alternata in terms of allergic disease burden.

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Epicoccum nigrum

Hydrophilic

Aw ≥ 0.90·Tertiary colonizer

Epicoccum nigrum is a cosmopolitan mold found primarily on decaying plant material outdoors but also colonizing water-damaged building materials indoors.

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Mucor amphibiorum

Hydrophilic

Aw ≥ 0.93·Tertiary colonizer

Mucor amphibiorum belongs to the Mucorales, a group of fast-growing, water-loving fungi that thrive under high moisture conditions.

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Penicillium chrysogenum

Xerophilic

Aw ≥ 0.78·Primary colonizer

Penicillium chrysogenum (famous as the original source of penicillin, the antibiotic that changed medicine) is also one of the most common indoor molds worldwide.

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Rhizopus stolonifer

Hydrophilic

Aw ≥ 0.93·Tertiary colonizer

Rhizopus stolonifer (commonly called bread mold) is the fast-growing fuzzy gray mold most people recognize from spoiling bread, fruit, and vegetables.

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Beyond the 36

Some commercial labs report 18 additional species beyond the standard EPA ERMI panel, primarily extra Aspergillus and Penicillium species, and a handful of additional water-damage indicators. They do not appear in the ERMI or HERTSMI-2 score, but the extra detail can help refine the moisture-niche picture when a lab provides it.

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