About Acremonium strictum
Acremonium strictum is one of the molds most often found in water-damaged building materials, frequently found alongside Stachybotrys chartarum and Chaetomium globosum in severely water-damaged drywall and wallpaper. Despite being classified as a Group 2 mold, its frequent association with water-damaged building materials makes it one of the more informative Group 2 species when it is elevated. Acremonium species are increasingly recognized as emerging opportunistic pathogens.
Ecology and water requirements
Acremonium strictum is classified as a tertiary colonizer in the ecological succession that follows water damage in indoor environments. Primary colonizers (xerophilic Penicillium and Aspergillus species) establish first on damp materials at relatively low water activity; secondary colonizers (Cladosporium) follow as moisture stabilizes; tertiary species like Acremonium strictum require sustained, high water activity (Aw 0.90 or above)[2] and typically appear after weeks to months of continuous wetness. Because of this requirement, its detection in indoor dust samples is one of the more diagnostic available signals of significant, sustained water intrusion[4], distinct from elevated humidity alone. The species cannot establish on materials that dry between wetting events; persistent water contact with cellulose-containing or other organic substrates is required.
Mycotoxin biology
Acremonium strictum produces a range of secondary metabolites with biological activity. The compounds documented in the literature for this species are listed in the chips below. Mycotoxin production is not uniform across all strains and is influenced by substrate, temperature, and water activity[3]. The same isolate may produce substantially different metabolite profiles on drywall paper versus wood versus settled dust[5]. DNA-based detection via the ERMI panel identifies species presence but does not directly measure mycotoxin presence; detection of a mycotoxin-producing species in household dust does not establish exposure to that mycotoxin at any specific concentration.
Detection in dust versus visual inspection
DNA-based detection of Acremonium strictum in settled household dust (the basis of the ERMI panel[1]) integrates spore material from current and recent growth in the home, capturing exposure history over weeks to months. A positive detection in dust does not necessarily indicate currently-active growth at the time of sampling; conversely, an active growth site can produce relatively low dust spore counts if the spores are not being aerosolized (sealed wall cavities, behind vapor barriers, or under flooring). Interpretation requires considering the dust signal alongside building inspection, occupant symptom history, and the broader pattern of species detected on the panel.
Where it’s typically found
Acremonium strictum is documented on the following substrates and locations:
- Water-damaged drywall
- gypsum board
- wallpaper; soil
- plant debris; commonly co-detected with Stachybotrys
Mycotoxins
Compounds documented as produced by Acremonium strictum (presence and quantity vary by chemotype, strain, and substrate):
Mycotoxin production is not uniform across all strains and is influenced by substrate, temperature, and water activity. Detection of a mycotoxin-producing species in household dust does not directly establish exposure to that mycotoxin at any specific concentration.
On your ERMI report
Acremonium strictum is one of the 10 EPA environmental reference species used to compute the SLG2 component of the ERMI score (sometimes labeled "Group 2" in EPA documentation). Group 2 species are commonly found in outdoor air; their levels are subtracted from the indicator-species sum, which means high outdoor-reference detections actually reduce the final ERMI. A low-level detection of Acremonium strictum is common, because these species are also found in outdoor air. Our interpretation report reads its level alongside the indicator species.
Related species
References
- Vesper SJ, McKinstry C, Haugland RA, et al. Development of an Environmental Relative Moldiness Index for U.S. homes. J Occup Environ Med. 2007;49(8):829–833.
- Pitt JI, Hocking AD. Fungi and Food Spoilage. 3rd ed. New York: Springer; 2009.
- Nielsen KF. Mycotoxin production by indoor molds. Fungal Genet Biol. 2003;39(2):103–117.
- Institute of Medicine. Damp Indoor Spaces and Health. Washington, DC: National Academies Press; 2004.
- Miller JD, McMullin DR. Fungal secondary metabolites as harmful indoor air contaminants: 10 years on. Appl Microbiol Biotechnol. 2014;98(24):9953–9966.